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spartan’14 program version 1.1.4 computational software package  (Wavefunction inc)

 
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    Wavefunction inc spartan’14 program version 1.1.4 computational software package
    Spartan’14 Program Version 1.1.4 Computational Software Package, supplied by Wavefunction inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/spartan+14+version+1%2E1%2E4+software+package/software+spartan%E2%80%9914+program+version+1+1+4+computational+software+package/pm37257024-253-38-45
    Average 90 stars, based on 1 article reviews
    spartan’14 program version 1.1.4 computational software package - by Bioz Stars, 2026-09
    90/100 stars

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    Article Title: Investigation of Novel Imidazole Analogues with Terminal Sulphonamides as Potential V600E-BRAF Inhibitors Through Computational Approaches
    Article Snippet: 1 Department of Chemistry, Faculty of Physical Sciences, Ahmad Bello University, P.M.B.1045, Zaria, Kaduna State, Nigeria 2 Department of Chemistry, Nigerian Army University, Biu, Borno State, Nigeria 3 Department of Biological Sciences, Ummaru Musa Yar′ Adua University, Katsina, Katsina State, Nigeria 4 Department of Pure and Industrial Chemistry, Bayero University, Kano, Kano State, Nigeria Abstract The V600E-BRAF protein kinase is a promising and essential therapeutic target in melanoma and other types of tumors.. However, its resistance to known inhibitors, as well as the side effects of some identified inhibitors, necessitates the search for new and potent inhibitors.. In this study, in-silico strategies such as Molecular-docking simulation, DFT (DensityFunctional-Theory) computations, and Pharmacokinetic evaluation were used to identify potential V600E-BRAF inhibitors from a set of 38 novel imidazole analogs with terminal sulphonamides.

    Article Title: Molecular modeling strategy to design novel anticancer agents against UACC-62 and UACC-257 melanoma cell lines
    Article Snippet: The energy of these molecules was minimized using Molecular mechanics (MM2) force field methods [24] and converted to 3D format using Spartan 14 Version 1.1.4 software package from Wavefunction Inc.

    Article Title: Computational evaluation of potent 2-(1H-imidazol-2-yl) pyridine derivatives as potential V600E-BRAF inhibitors
    Article Snippet: The 2D structures were converted into the 3D structures utilizing the Spartan 14 Version 1.1.4 software package from Wavefunction Inc.



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